Common Heartburn Medication, Proton Pump Inhibitors, May Injury Kidneys


More evidence that a type of heartburn medication known as proton pump inhibitors (PPIs) may be associated to long-term kidney damage, according to  the study, “Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease,” published in JAMA Internal Medicine.

“This is an important study because millions of Americans are on proton pump inhibitors and have been for many years,” Kenneth DeVault, MD, a Mayo Clinic gastroenterologist, said in a news release.

Medications like Prilosec, Nexium, and Prevacid belong to the class of PPIs that are one of the most commonly prescribed medications in the United States. PPIs treat heartburn and acid reflux by lowering the amount of acid produced by the stomach. Their use has been linked to acute interstitial nephritis, but less is known about the association between PPI use and chronic kidney disease (CKD).

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